Leo was considered less handsome than his brother and had light eyes that resembled his mothers.
He attended Hogwarts from 1925 to 1931 and was sorted into Hufflepuff House, unlike his brother and father (Slytherin). His mother and younger sister did share his house.
After Leo's father Herbert dies in 1936, his brother Nigellus takes over the shop Borgin & Burkes. He retires however in 1956 and Leopold takes over. Leopold runs the shop for 28 years untill 1984, when Nigellus dies and Leopold retires, too, out of grief. He was the last Burke to run the shop.